This study examined the effect of compensation on workers’ satisfaction in Nkwen Baptist Hospital, Bamenda. Compensation remains a critical factor in enhancing employee motivation, commitment, and overall job satisfaction, particularly within healthcare institutions where employee performance directly influences service quality and patient outcomes. Despite the importance of compensation, many healthcare workers experience challenges related to inadequate financial and non-financial rewards, which may negatively affect their level of satisfaction and productivity. The study was guided by two specific objectives: to ascertain the influence of financial compensation on workers’ satisfaction and to explore the effect of non-financial compensation on workers’ satisfaction in Nkwen Baptist Hospital, Bamenda. A descriptive survey research design was adopted for the study. Data were collected from employees of the hospital using a structured questionnaire. The data obtained were analyzed using descriptive and inferential statistical techniques to determine the relationship between compensation and workers’ satisfaction. The findings revealed that financial compensation, including salaries, bonuses, and allowances, has a significant positive influence on workers’ satisfaction. The study also found that non-financial compensation, such as recognition, promotion opportunities, supportive work environments, and career development opportunities, significantly contributes to employee satisfaction. The study concluded that both financial and non-financial compensation are important determinants of workers’ satisfaction in Nkwen Baptist Hospital. The study recommends that hospital management review and improve its compensation policies by ensuring competitive financial rewards and strengthening non-financial incentive systems to enhance employee satisfaction, motivation, and organizational performance.